By Charles R. Cantor
A different exploration of the foundations and techniques underlying the Human Genome undertaking and smooth molecular genetics and biotechnology-from best researchers
In Genomics, Charles R. Cantor, former director of the Human Genome venture, and Cassandra L. Smith supply the 1st fundamental assessment of the thoughts and applied sciences in the back of the Human Genome undertaking and the sector of molecular genetics and biotechnology. Written with more than a few readers in mind-from chemists and biologists to laptop scientists and engineers-the ebook starts off with a assessment of the fundamental houses of DNA and the chromosomes that package deal it in cells. The authors describe the 3 major ideas utilized in DNA analysis-hybridization, polymerase chain response, and electrophoresis-and current a whole exploration of DNA mapping in its many various varieties. via explaining either the theoretical ideas and functional foundations of contemporary molecular genetics to a large viewers, the publication brings the clinical group towards the last word target of figuring out the organic functionality of DNA. Genomics features:
- Topical association inside chapters for simple reference
- A dialogue of the constructing equipment of sequencing, similar to sequencing via hybridization (SBH) within which facts is learn via phrases rather than letters
- Detailed reasons and significant reviews of the numerous kinds of DNA maps that may be generated-including cytogenic and restrict maps in addition to interspecies mobile hybrids
- Informed predictions for the way forward for DNA sequencing
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