Download E-books Telomerase Inhibition: Strategies and Protocols PDF

By Lucy G. Andrews, Trygve O. Tollefsbol (auth.), Lucy G. Andrews, Trygve O. Tollefsbol (eds.)

Due partly to the selective nature of telomerase inhibition as an anticancer strategy, the sphere has elevated significantly some time past decade. the hot advances in tools of telomerase inhibition surround many various parts of analysis together with molecular biology, phone biology, biochemistry, oncology and gerontology. Telomerase Inhibition presents equipment and protocols for these researchers. The strategies defined during this ebook should still give you the researcher with a various and finished set of instruments with which to review telomerase inhibition. Leaders within the box offer lately built tools that experience frequent program resembling concentrating on the telomerase holoenzyme, its RNA template and different parts linked to telomerase task. extra tools concerning the screening of telomerase inhibitors and telomerase inhibition mixed with different chemotherapeutic brokers are provided. this article, at the innovative of the sphere, will offer investigators with the latest equipment utilized to the increasing box of telomerase inhibition.

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Download E-books Quinones and Quinone Enzymes Part B PDF

By Sies Helmut (Ed.), Packer Lester

Quinones are participants of a category of fragrant compounds with oxygen atoms bonded to the hoop as carbonyl teams. This quantity covers extra medical features of quinines, akin to anticancer homes, in addition to their position in meals and in age-related illnesses. *Mitochondrial Ubiquinone and Reductases *Anticancer Quinones and Quinone Oxido-Reductases *Quininone Reductases: Chemoprevention, meals *Quinones and Age-Related ailments

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Download E-books Extracellular Nucleic Acids PDF

By Wen-Chi Chiang, Tim Tolker-Nielsen (auth.), Yo Kikuchi, Elena Y. Rykova (eds.)

Extracellular nucleic acids have lately emerged as very important gamers within the fields of biology and the scientific sciences. within the final a number of years, extracellular nucleic acids were proven to be fascinated by not just microbial evolution as genetic components but additionally to have structural roles in bacterial groups, comparable to biofilms. Circulating DNA and RNA were present in human blood and anticipated to be beneficial as non-invasive markers for the prognosis of a number of ailments. moreover, extracellular nucleic acids have attracted cognizance as lively modulators of the immune approach of upper organisms, together with people. This e-book covers the majority of the newly constructing fields regarding extracellular nucleic acids, together with these of easy biology, ecology and the scientific sciences, and gives readers with the most recent wisdom on them.

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Download E-books Medizinische Mikrobiologie (Duale Reihe) (German Edition) PDF

By Herbert Hof

Erreger, Abläufe, Krankheitsbilder: Die Duale Reihe Medizinische Mikrobiologie verschafft dir den Überblick. Hier findest du das gesamte relevante Wissen zu den Fächern Bakteriologie, Virologie, Mykologie, Parasitologie, Immunologie, Klinische Infektiologie und Hygiene.

- Schnell zurechtfinden: Die Inhalte sind hervorragend strukturiert, bei klarem, übersichtlichem format
- Auch komplizierte Sachverhalte sind maximal verständlich geschrieben
- Zahlreiche Abbildungen und Grafiken veranschaulichen Erreger und Krankheitsbilder
- Online-Extras: Filme zur hygienischen und chirurgischen Händedesinfektion

Jederzeit zugreifen: Der Inhalt des Buches steht dir auch electronic in der Online-Plattform eRef zur Verfügung. Zugangscode im Buch.

Duale Reihe: Ausführliche Lehrbücher zum vertiefenden Lernen, die du auch als Kurzlehrbuch nutzen kannst. Viele didaktische Elemente sowie Abbildungen und Tabellen im Haupttext erleichtern dir das Lernen. Mit den integrierten klinischen Fallbeispielen hast du auch immer den notwendigen Praxisbezug.
Der textual content in der Randspalte dient der gezielten Prüfungsvorbereitung. Hier findest du die wichtigsten Aussagen des Haupttextes gebündelt, dabei hast du die zugehörigen Abbildungen und Tabellen immer im Blick.

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Download E-books Plant Genome Diversity Volume 1: Plant Genomes, their Residents, and their Evolutionary Dynamics PDF

By Lex E. Flagel, Benjamin K. Blackman (auth.), Jonathan F. Wendel, Johann Greilhuber, Jaroslav Dolezel, Ilia J. Leitch (eds.)

In this well timed new 2-volume treatise, specialists from worldwide have banded jointly to supply a first-of-its-kind synopsis of the intriguing and fast-paced box of plant evolutionary genomics. In quantity I of Plant Genome variety, an replace is equipped on what we have now realized from plant genome sequencing initiatives. this can be by means of extra concentrated chapters at the numerous genomic “residents” of plant genomes, together with transposable parts, centromeres, small RNAs, and the evolutionary dynamics of genes and non-coding sequences. realization is attracted to advances in our knowing of plant mitochondrial and plastid genomes, in addition to the importance of duplication in genic evolution and the non-independent evolution between sequences in plant genomes. eventually, quantity I offers an advent to the colourful new frontier of plant epigenomics, describing the present kingdom of our wisdom and the evolutionary implications of the epigenomic landscape.

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Download E-books Engineered Zinc Finger Proteins: Methods and Protocols PDF

By Mital S. Bhakta, David J. Segal (auth.), Joel P. Mackay, David J. Segal (eds.)

Among the numerous varieties of DNA binding domain names, C2H2 zinc finger proteins (ZFPs) have confirmed to be the main malleable for growing customized DNA-binding proteins. In Engineered Zinc Finger Proteins: tools and Protocols, specialist researchers from essentially the most lively laboratories during this box current distinct equipment, counsel, and views. the amount includes sections masking the engineering of ZFPs, equipment for the production, evaluate, and supply of man-made transcription elements (ATFs), equipment for the production and overview of zinc finger nucleases (ZFNs), and a set of different purposes and assays past ATFs and ZFNs, together with zinc finger transposases and ChIP-seq method among different matters. Written within the hugely winning tools in Molecular Biology™ sequence layout, chapters comprise introductions to their respective subject matters, lists of the required fabrics and reagents, step by step, without problems reproducible laboratory protocols, and notes on troubleshooting and keeping off recognized pitfalls. accomplished and state-of-the-art, Engineered Zinc Finger Proteins: equipment and Protocols goals to assist either pro practitioners and new investigators with its important equipment and insights as they search to create the following iteration of engineered ZFPs and applications.

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Download E-books Biology of Copepods: Proceedings of the Third International Conference on Copepoda PDF

By Z. Kabata (auth.), Geoffrey A. Boxshall, H. Kurt Schminke (eds.)

This quantity comprises the lawsuits of the 3rd foreign convention on Copepoda, held on the British Museum (Natural historical past) in London in the course of August 1987. The vital subject of the convention used to be the biology of marine planktonic copepods, even if the clinical programme used to be super diverse reflecting the wide variety of existence kinds followed through copepods. the 3 invited symposia held in the course of the convention focussed cognizance on specific topical parts of study in the box of marine plankton, and likewise supplied studies of selected facets of copepod biology. those symposia have been hugely profitable. The papers they contained have been either informative and stimulating and so they carry to this quantity a long-lasting importance. every one symposium was once organised by means of its chairman; Bruce Frost (University of Washington) selected the stability of subject matters, chosen the audio system and brought the consultation on 'The biology and taxonomy of Calanus', Roger Harris (Marine organic organization) played an analogous very important function for 'Experimental stories: cost techniques in box populations of planktonic copepods', and Howard Roe (Institute of Oceanographic Sciences) for 'Oceanic and deep-sea copepods'. The impression of those papers might be a lot stronger via the massive variety of top of the range contributed and poster papers on marine plankton and by way of the invited overview of 'Copepod luminescence' by means of Peter Herring (Institute of Oceano­ photo Sciences). The interesting evaluation of 'Copepod eyes' by means of Mike Land FRS (University of Sussex) isn't really released here.

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Download E-books Animal Cell Culture (Methods in Molecular Biology Vol 5) PDF

By Jeffrey W. Pollard, John M. Walker

Animal telephone tradition, the newest quantity in Humana's hugely winning equipment in Molecular Biology sequence, presents certain functional concepts for the tradition of a wide spectrum of easy mobilephone cellphone varieties. Chapters provide hands-on tools for developing mammalian fibroblastic mobilephone cultures and conserving tradition stipulations for epithelial, neuronal, and hematopoietic cells between others. cognizance is given to the variety of tradition media and extracellular matrices had to retain the differentiated services of the classy cells. The book's distinct energy lies in its descriptions of tradition concepts for either dwelling and stuck cells. Chapters hide strategies resembling: • cinematographic research • in situ mRNA hybridization • immunofluorescence • immunoelectron microscopy • somatic telephone hybridization • DNA transformation • insect mobilephone tradition • production of hybridoma cellphone traces • monoclonal antibody recommendations • new, really good methodologies. an invaluable appendix lists the main commonplace tradition media. entire in scope and insurance, and punctiliously updated, Pollard and Walker's distinctive instruction manual on ANIMAL mobile tradition is an quintessential source for either the beginner and the professional specialist.

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Download E-books Low Temperature Biology of Foodstuffs: Recent Advances in Food Science: Low Temperature Biology of Foodstuffs v. 4 PDF

Low Temperature Biology of Foodstuffs describes the concept that of low temperature biology and its program within the nutrition undefined.

This booklet is split into 23 chapters and starts off with descriptions of numerous low temperature strategies, akin to nucleation, ice crystal progress, and freezing. The succeeding chapters take care of the protecting mechanisms in frost-hardy vegetation, the physico-chemical adjustments in meals in the course of freezing and garage, and the effect of chilly garage, freezing, and thawing microbial and inhabitants of a number of foodstuffs. those issues are by means of discussions of the rules of freezing and low-temperature garage of fruit and greens. different chapters discover the method of gelation, the freezing and frozen garage of fish muscle and meat. the ultimate chapters inspect the subjective reviews of frozen nutrition caliber, together with their physico-chemical properties.

This booklet will end up helpful to meals scientists and brands.

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